Introduction
Mitochondria contain electron transport chain and transfers electrons to oxygen by a process called oxidative phosphoryltion. This releases energy for the production of ATP by forming pH and electrical gradient across the mitochondrial membrane. This is not the only function that the mitochondria have. The other functions include: ATP for cellular energy, metabolize fats, carbs and amino acids, reproduce themselves and make free radicals to name a few. Apoptosis is important in development and disease and human disease can be the result of a malfunction. Mitochondria are from the mother and contain their own DNA. Mitochondrial DNA encodes close to three percent of proteins.
History
In 1988 the first human disease associated with mtDNA deletions was reported. The person had brain and muscle diseases with sympathy. Kearns-Sayre Syndrome causes a person to lose full function of heart, eye and muscle movements. This is just one of the disease mitochondrial that can happen to one who suffers from it. Kearns-Sayre Syndrome is also thought to be one of the biggest factors in the aging process and associated pathologies. Living with diseases mitochondrial is different for each person depending on their degree of the disease. Diseases mitochondrial can cut off the needed energy supply for cells.
Features
In 1988, the first human disease associated with mtDNA deletions was reported. The person had brain and muscle diseases with sympathy. Kearns-Sayre Syndrome causes a person to lose full function of heart, eye and muscle movements. This is just one of the diseases mitochondrial that can happen to one who suffers from it. Kearns-Sayre Syndrome is also thought to be one of the biggest factors in the aging process and associated pathologies. Living with diseases mitochondrial is different for each person depending on their degree of the disease. Diseases mitochondrial can cut off the needed energy supply for cells. Some of the different diseases mitochondrial include Leigh syndrome, MELAS, MERRF, MNGIE, NARP, Pearson syndrome and PEO. The main symptoms of mitochondrial sympathy include muscle weakness and wasting and exercise intolerance. It is not a disease that can be caught from one person to the next and while it can run in failed, it can strike each person differently.Depending on what diseases mitochondrial you have, different parts of your body will be affected. Some people lose much of the muscle control in their legs and end up in a wheel chair. If affects anyone and there is no age limit or time frame.
Tips and comments
There can be some help for different diseases hearing impairment can be helped with the aid of hearing aids. If you suffer from migraines, medicine can be prescribed to help with those. Seizures, that often go along with migraines in those that suffer from diseases mitochondrial can be stopped with seizure medicine. If babies have mitochondrial diseases they usually have more issues than those that get it at an older age. Babies sometimes never have the chance to develop their muscle control. Having early intervention can help get the person affected the physical therapy they need and might help at slowing the process. There is no known cure even though research is being conducted.
